Imagine your body has a bucket that collects histamine from various sources: Dietary histamine Histamine released by mast cells due to genuine allergies Histamine released due to sulfite-induced mast cell degranulation When this bucket overflows, you experience allergy symptoms
In the latter, cysteine originates from the reduction of cystine transported into the cell by cystine/glutamate antiporter (system Xc , xCT) [26]
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doi: 10.1111/hepr.12456
Osman AA, Arslan E, Bartels M, Michikawa C, Lindemann A, Tomczak K, et al